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NO. 24529

Biologically active compounds from Malaysian Zingiberaceae

Hasnah, MS; Ahmad, AR
Department of Chemistry; Faculty of Science; University Teknologi Malaysia; Johor; Malaysia

Eight Asian Symposium on Medicinal Plants, Spices and Other Natural Products, 12-16 June 1994, Malacca, Malaysia

Several biologically active compounds have been isolated from Malaysian Zingiberaceae. These included alkaloid piperine from Achasma megalocheilos and Alpinia purpurata, sesquiterpene zerumbone from Zingiber ottensii and Zingiber zerumbet, germacrone from Curcuma xanthorrhiza and Curcuma phaeocaulis, diterpene labda 8(17), 12-diene-15, 16-dial2 from Hornstedtia scyphifera and Zingiber spectabilis, labdane butenolides coronarin C, and 14(- isocoronarin D from Hedychium coronarium and 1'-acetoxychavicol acetate3 from Alpinia conchigera and Alpinia galanga. Isolation and identification of these compounds were discussed.

Availability :
Forest Research Institute Malaysia (FRIM), Jalan FRIM, Kepong Karung Berkunci 201, 52109 Kuala Lumpur, Selangor, Malaysia; phone: (60) (3) 627 42633; fax: (60) (3) 627 65531
Email: philip@frim.gov.my

NO. 25432

Antioxidant and antitumour promoting activity of Malaysian species of Zingiberaceae

Habsah, M; Lim, YM; Amran, A; Jasril, M; Lajis, NH; Ali, AM; Kikuzaki, H; Nakatani, N; Rahman, AA; Ghafar
Department of Chemistry, Universiti Putra Malaysia, 43400 Serdang, Selangor

Seminar on Medicinal and Aromatic Plants: Towards Bridging Science and Herbal Industry, 12-13 September 2000, Forest Research Institute of Malaysia (FRIM), Selangor

Species in the family Zingiberaceae have been widely used in the formulation of Malaysian traditional medicine. From reports produced, there is evidence that antioxidant and antitumour promoting activities exist in several species of the genera Curcuma and Zingiber. This interesting discovery plus the availability of a good collection of species at PSGT, Universiti Putra Malaysia, prompted us to investigate the antioxidant and antitumour promoting activities from other genera. In this study, a total of 33 species from the genera Alpinia, Costus, Zingiber, Hedychium, Achasma, Nicolaia, Curcuma, Geanthus and Amomum were screened for antioxidant activity using the FTC method. All species exhibited higher activity than the known natural antioxidant (x-tocopherol). A total of 27 samples of crude extract (18 dichloromethene extracts and 9 methanolic extracts) were also tested for in vitro antitumour promoting activity using the EBV-EA assay. Of these, 44% of dichloromethene extracts and 33% of methanolic extracts were highly active at the concentration of 20 mg/ml. Therefore, the significant antioxidant and antitumour promoting activity properties of the Zingiberaceous extracts is particularly relevant to their use as a major ingredient in the preparation of 'Jamu'. Accordingly, this could imply the inhibition of cellular oxidation that was linked to heart disease, ageing and cancer.

Availability :
Forest Research Institute Malaysia
Email: philip@frim.gov.my

NO. 51498

Radical scavenging activity of flavonoids isolated from Hedychium thyrsiforme

Jasril; Mooi, LY; Lajis, NH; Ali, AM; Sukari, A; Rahman, AA; Othman, AG; Kikuzaki, H; Nakatani, N
Department of Chemistry, University Putra Malaysia; Serdang, Selangor, Malaysia

Proceedings International Seminar on Natural Products Chemistry and Utilization of Natural Resources, June 5 – 7, 2001, Universitas Indonesia, Depok Indonesia; Kosela, S et al. (eds); Depok, Universitas Indonesia, 2001; p 274-276

Five flavonoids were isolated from the rhizome parts of Hedychium thyrsiforme. They were 3, 7, 4'-trimethoxy-5-hydroxyflavone (1), 3, 4'-dimethoxy-5, 7-dihydroxy-flavone (2), 5, 7, 4'-trimethoxy-3-hydroxyflavone (3), 3, 5, 7, 4'-tetramethoxyflavone (4) and 7, 4'-dimethoxy-3, 5-dihydroxyflavone (5). Compound 3 and 5 were found to be free radical scavengers with IC50 values of 30.2 and 37.4 µg/ ml, respectively. The structures of flavonoids were established based on special studies.

Availability :
PROSEA Network Office

NO. 107150

Utilization of zingiberaceae as a traditional medicine material by people in Lembah Delapan, Bengkulu
Pemanfaatan jahe-jahean (Zingiberaceae) sebagai bahan obat tradisional oleh masyarakat Lembah Delapan, Bengkulu

Siagian, M.H.; Sunaryo
Research and Development Centre for Biology (RDCB); Bogor; Indonesia

Laporan Teknik Proyek Penelitian Pengembangan dan Pendayagunaan Potensi Wilayah [Technical Report of the Development Research and Utilization of Area Potential Project]; Tahun Anggaran 1995/1996; Puslitbang Biologi; Bogor; 1996; p.39-44

Availability :
Research and Development Centre for Biology (RDCB); Bogor; Indonesia

NO. 101795

Medicinal plants of the Zingiberaceae
Tumbuhan obat famili Zingiberaceae

Darwis, S.N; Madjo Indo, A.B.D; Hasijah, S
Central Research Institute for Industrial Crops (CRIIC); Bogor; Indonesia

Seri Pengembangan [Development Series] No.17 (1992); Pusat Penelitian dan Pengembangan Tanaman Industri Bogor; ?p

Availability :
Central Research Institute for Industrial Crops (CRIIC); Bogor; Indonesia

NO. 12586

Effects of Thai plant extracts on the oriental fruit fly II. Repellency

Department of Entomology; Kasetsart University; Bangkok; Thailand

Kasetsart Journal (Natural Sciences) 22(1):56-61(1988)

Availability :
Thai National Documentation Centre;Bangkok;Thailand

NO. 91733

The flora of the Philippines project and its role in plant conservation

Madulid, DA
Syluatrop Technical Journal of Philippine Ecosystem and Natural Resources 5 (182): 97-100 (1995)

The "Flora of the Philippines" project aims to protect endangered species of plants. It is an organization which research on rare plants and propagate and study them.

Availability :
Ecosystems Research and Development Bureau; Forestry Campus

NO. 27070

Studies on chemical constituents of some medicinal plants of Zingiberaceae

Hasnah, MS; Norazah, H; Rohaiza, S.
Department of Chemistry; Faculty of Science; Universiti Teknologi Malaysia; 81310 Skudai; Johore

International Science Congress 2005; 3-6 August 2005; Kuala Lumpur

Chemical components of several medicinal plants of Zingibearceae have been investigated. Among them are the plants of the genera of Zingiber, Hedychium and Alpinia. A variety of bioactive constituents have been isolated using various chromatographic techniques and identified spectroscopically from these plants. Phenylpropanoids, sesquiterpenoids, diterpenoids, phenolics, and diarylheptanoids have been found to be the constituents of these plants, which provide some interesting biological activities such as antimicrobes, antioxidant, anticancer, antityrosinase, anti-inflammatory and cytotoxicity. Trans-farnesol, zerumbone, zingiberene and p-sesquiphellandrene were among the common sesquiterpenoids characterized from Alpinia and Zingiber. The labdane type diterpenoids were the main class of constituents identified from the Hedychium and Alpinia species, while diarylheptanoids, and phenolics were isolated from the Alpinia and Zingiber plants.

Availability :
Forest Research Institute Malaysia

NO. 16262

The Genus Hedychium in Thailand

Sirirugsa, P.
Prince of Songkhla university research abstracts. 1987-1992. P.577.

All specimens of the genus Hedychium from the major herbaria in Europe, Japan as well as from the herbaria in Thailand and the fresh material form the natural habitats have been studied. Nineteen species of the genus Hedychium in Thailand are recognized, five of which are new to science. A key to the Thai species with the descriptions, illustrations as well as distribution, ecology and vernacular names are provided.

Availability :
Thai National Documentation Centre, Thailand Institute of Scientific and Technological Research